Virulence factors of enteropathogenic Escherichia coli
نویسندگان
چکیده
منابع مشابه
Transcriptional inhibitor of virulence factors in enteropathogenic Escherichia coli.
The type III secretion system (TTSS) is a key virulence mechanism of many important gram-negative bacterial pathogens. The TTSS is conserved among different bacterial pathogens, and mutations and deletions to the system significantly decrease virulence, making the TTSS an important potential therapeutic target. We have developed a high-throughput assay to search for inhibitors of the TTSS. We s...
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Enteropathogenic Escherichia coli (EPEC) remains an important cause of diarrheal disease worldwide. Research into EPEC is intense and provides a good virulence model of other E. coli infections as well as other pathogenic bacteria. Although the virulence mechanisms are now better understood, they are extremely complex and much remains to be learnt. The pathogenesis of EPEC depends on the format...
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Enteropathogenic and Enterohemorrhagic Escherichia coli Virulence Gene Regulation Jay L. Mellies,* Alex M. S. Barron, and Anna M. Carmona Biology Department, Reed College, 3203 S.E. Woodstock Boulevard, Portland, Oregon 97202; Oregon Health Sciences University, L215, 3181 S.W. Sam Jackson Park Rd., Portland, Oregon 97239; and School of Public Health, University of California, Berkeley, 140 Warr...
متن کاملRpoS role in virulence and fitness in enteropathogenic Escherichia coli
Enteropathogenic Escherichia coli (EPEC) is a diarrheagenic pathogen that afflicts infants in developing countries. The most important virulence trait of EPEC is its ability to intimately adhere to cells in the small intestine, and to elicit diarrhea. The alternative sigma factor RpoS is involved in the virulence of several bacterial species. RpoS coordinates the general stress response and acc...
متن کاملLack of virulence factors in Escherichia coli strains of enteropathogenic serogroups isolated from water.
Thirty-eight Escherichia coli strains belonging to 14 human enteropathogenic serogroups were isolated from 33 of 208 water samples studied. No virulence factor or virulence-related gene sequences were found in any of the 38 strains analyzed. The results point out the importance of detecting specific virulence factors before incriminating water as a source of human diarrhea.
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 1988
ISSN: 0022-2615,1473-5644
DOI: 10.1099/00222615-26-1-1